Photo-Oxidation of 2-Methylamino-3-(1-piperidinylmethyl)-1,4-naphthoquinone.

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Synthesis and Antimicrobial Activity of Some 2-[(4-Substituted-Phenyl-3-Chloro-Azetidin-2-One)-5-(2'-Methylamino-4-Phenyl-1', 3'-Thiazolyl-]-1, 3,4-Thiadiazoles

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2-Chloro-3-(4-chloro­benzamido)-1,4-naphthoquinone

The naphthoquinone ring is almost perpendicular [dihedral angle 71.02 (3)°] to the phenyl group of the title compound, C(17)H(9)Cl(2)NO(3), while the dihedral angle between the amide group and the 4-chloro-phenyl ring is 21.9 (2)°. The conformation of the N-H and C=O bonds are anti to each other. N-H⋯Cl hydrogen bonds link the mol-ecules into chains in the a-axis direction. In addition, these c...

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synthesis and antimicrobial activity of some 2-[(4-substituted-phenyl-3-chloro-azetidin-2-one)-5-(2'-methylamino-4-phenyl-1', 3'-thiazolyl-]-1, 3,4-thiadiazoles

a new 2-[(4-substituted-phenyl-3-chloroazetidin-2-one)-5-(2'-methylamino 4-phenyl-1', 3'-thiazolyl-]-1, 3, 4-thiadiazoles, 5(a-n) were synthesized from 2-substituted-benzylideneamino-5-[2'-methylamino-4'-phenyl-1',3'-thiazolyl]-1,3, 4-thiadiazole, 4(a-n) using 2-amino-4phenyl-1, 3-thiazole as a starting material. the synthesised compounds have been screened in vitro for their antimicrobial acti...

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Aldose reductase catalyzes the oxidation of naphthalene-1, 2-dihydrodiol for the formation of ortho-naphthoquinone.

The oxidation of naphthalene-1,2-dihydrodiol (ND) to o-naphthoquinone (NQ) in the lens is believed to be responsible for the formation of cataracts in naphthalene-fed rats. Studies using either recombinant rat lens (RLAR) or human muscle aldose reductase (HMAR) incubated in vitro with ND in the presence of NAD(P) verified that aldose reductase (EC 1.1.1.21) is the dihydrodiol dehydrogenase that...

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C 1 NQR , Crystal Structure , and Pyroelectricity of 2 , 3 - Dichloro - l , 4 - naphthoquinone *

The C1 NQR spectra of the two phases (phases I and II) of 2,3-dichloro-l,4-naphthoquinone were studied from 77 to 394 K. The crystal structure determination of the triclinic phase (phase I) was refined by single crystal X-ray diffraction. Phase I crystallizes in the space group C/-P1. The unit cell (Z = 4) has the dimensions a = 1614.3(4) pm, 6 = 828.1 (3) pm, c = 733.2(3) pm, a = 67.02(l)°, /?...

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ژورنال

عنوان ژورنال: Chemical and Pharmaceutical Bulletin

سال: 1994

ISSN: 0009-2363,1347-5223

DOI: 10.1248/cpb.42.2360